Investigation Service

Laboratory Division

Confocal Laser Scanning Microscope (CLSM)

Confocal laser scanning microscope broadly applied in biological studies ranging from cellular biology, genes, and also macromolecular biology. Especially for applications that require high-resolution images and the ability to capture only the focus area and specify the required sample layer depth.

Thick Specimen imaging

cell culture, tissue sample from human, animal or plants

Live cell imaging

Developmental study, expression over time-lapse study, pharmacokinetic study, Human or Animal Fertilization study

3D imaging

2D & 3D imaging, 3D time-lapse (4D) imaging

Multi-dyes immune-labeling imaging

Co-localization study, Immunocytochemistry, Immunohistochemistry, cell-signaling study, protein-labeling expression

Liquid Chromatography – Tandem Mass Spectrometry (LC-MS/MS)

Liquid chromatography-mass spectrometry (LC-MS) is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry (MS). This technique is very specific and useful for analyzing non-separable or partial mixtures. The analysis results were shown in the form of the relationship between the time required for the substance to pass through the column and the absorbance or the graph showing Relative abundance to confirm the analytical.

Real-Time PCR

Real-time PCR is an advanced instrument used to amplify DNA sequences that examine the amount of DNA/cDNA that can be increased at each cycle while the reaction is ongoing, which has a fluorescent signal.

Flow Cytometer

Flow Cytometry is a technique for detecting and identifying physical and chemical characteristics of a population of cells or particles such as cell size, complexity of intracellular components, protein or substance analysis.

Application:
Leukemia and hematocystic identification for chemotherapy treatments
Basophil activation test for allergen
Study of cancer cell apoptosis and cell cycle
Diagnosis of primary immunodeficiency of T and B cell defect, by lymphocyte counting and neutrophil function test

Ultra High Pressure Liquid Chromatography (UHPLC)

UHPLC is similar to HPLC, in that it is a technique used to separate different constituents of a compound. The different technique is UHPLC used shorter column, less quantity of substance analyzed used, reduced time, and reduced the number of chemicals used as the moving phase in the analysis providing better separation.

Application:
Drug analysis
Determination of types and quantity of sugar in extracts
Analysis of composition of medicinal extracts
Analysis of pesticide residues in fruit and vegetable samples
Quantitative analysis of narcotics and various toxic substances